Avengers: Doomsday, Secret Wars, and Post-SW MCU Plans

Avengers: Doomsday and Secret Wars are not the last Avengers films; the franchise will continue with retooled team-ups.
Marvel is already planning another Avengers storyline, possibly featuring Annihilus and the Annihilation Wave.
Key roles in Doomsday: Sentry will be passive until a crisis with Yelena, Doctor Strange will address multiverse incursions, and Sebastian Stan’s Bucky will mediate between the Avengers and Thunderbolts.
Post-Secret Wars, Marvel will likely have multiple Avengers teams, including Young Avengers.
Deadpool and Doctor Doom will play key roles in Doomsday and beyond.

What Happened:

Avengers: Doomsday and Secret Wars are not the final Avengers films. Marvel will continue to use the "Avengers" brand for smaller team-based stories and large, world-ending crossovers.
A new cosmic storyline is planned possibly involving Annihilus and the Annihilation Wave.
Doctor Strange will deal with multiversal incursions in Doomsday, alongside Clea.
Bucky Barnes will play a significant role in mediating between the Avengers and Thunderbolts in Doomsday.

Sentry: Appears calm but becomes active when Yelena is in danger.
Doctor Doom: Will pursue Steve Rogers in Doomsday.
Shuri: Will seek the help of Namor and the Atlanteans to fight Doom.
Deadpool: Has a small role in Doomsday, with more involvement in Secret Wars.
The MCU’s future could see multiple Avengers teams, with Young Avengers confirmed.

Captain America (Sam Wilson), The Falcon (Danny Ramirez), The Vision, Captain Marvel, Shang-Chi, Black Panther, Ant-Man, and Hulk are expected to form the next Avengers lineup.
Other potential future villains: Mephisto, Celestials, and Masters of Evil.

The Avengers brand will undergo changes after Secret Wars, with plans to evolve the franchise to include both large-scale team-ups and smaller, focused stories.
Regarding Deadpool's involvement in Doomsday, it was teased that audiences will finally understand why Thor was crying.